Thymic seminoma

Mediastinal seminoma associated with multilocular thymic cyst

An asymptomatic 26-year-old man received an annual medical check-up, and chest X-ray showed a protrusion of the aortopulmonary window. Chest computed tomography (CT) revealed an anterior mediastinal tumor and cysts with thin wall and septum enhancement. The preoperative diagnosis was cystic thymoma or malignant lymphoma. We performed total resection of the tumor through a median sternotomy. The...

Primary thymic seminoma in a 32-year-old female.

Orchitis reveals an extragonadal primary mediastinal thymic seminoma: a coincidence or not?

BACKGROUND Mediastinal thymic seminomas are rare male germ cell tumors with extragonadal origin that appear predominately with a cystic appearance. CASE PRESENTATION A 22-year-old male was referred to our department for further investigation of a mediastinal mass discovered incidentally during routine chest X-ray. The patient has denied any symptoms including dyspnea, chest pain, cough, fever...

Hypothesis: when is a seminoma not a seminoma?

A xenograft line, HX 53, has been established in immune-suppressed mice from a specimen of a lymph node metastasis in a patient with a histological diagnosis of seminoma but with markedly raised circulating levels of alpha-fetoprotein. Histological, immunocytochemical, and ultrastructural studies of this xenograft line have suggested that a solid variant of yolk sac carcinoma may exist, which m...

Giant intra-abdominal seminoma.

T susceptibility to malignancy of an undescended testis is well established. We report a 56-year old patient with giant intraabdominal seminoma of right undescended testis with no lymph node or distant metastasis, and normal left testis. The tumor was completely excised. The late presentation and size of the tumor were discussed. The patient is now 40 months postoperatively with no evidence of ...